BeneSpore™
A BV379 Probiotic that is a clinically supported, spore-forming Bacillus velezensis for digestive health.
Durability you can trust. Digestive support they can feel.
BV379 is a robust probiotic that forms protective spores, allowing it to survive harsh processing, long storage, and the acidic gut environment. This ensures consistent delivery of live CFUs in every serving.
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Suitable for a wide range food and dietary supplements with broad ingredient compatibility
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Produces a wide variety of digestive enzymes including protease, amylase, and cellulase
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Non-GMO and made without allergens
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Shelf stable for up to 36 months & thermostable- no refrigeration required
Clinical Trial Results
BeneSpore™ BV379 supplementation at 2 billion CFU/day for 8 weeks increased the proportion of participants showing improvement in abdominal bloating, compared to placebo.
The odds of an improvement were statistically significantly higher in the BV379 group compared to placebo (odds ratio = 2.9; P = .044, chi-square test)
Durability During Food Processing
Because BeneSpore™ Bacillus velezensis BV379 forms spores as part of its life cycle, it is naturally durable. The spore coat protects Bacillus much like a seed coat protects the viability of a plant seed. The Bacillus spore thus stands up to harsh manufacturing conditions and a wide variety of food, powdered protein, and beverage formulations. Bacillus velezensis BV379 is highly heat stable and survives acidic conditions, meaning CFUs are delivered to the final product.
Shelf stability at room temperature
Bacillus spores are not only durable through manufacturing, but also remarkably stable during long term storage, without
the need for refrigeration. Stability at room temperature means BV379 can be used in a wider range of shelf-stable food and
beverage products. BV379 carries a 36−month shelf-life when stored at room temperature.
Viability
The durability of the spore also means that Bacillus will survive transit through the human gastrointestinal tract without further encapsulation to deliver viable CFUs to the consumer. Bacillus velezensis BV379 is stable at an acidic pH as low as 2 for at least 6 hours. Additionally, BV379 is stable in bile containing environments such as those encountered in the human gut.1
